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Unraveling the complexity of amyloid polymorphism using gold nanoparticles and cryo-EM
Increasing evidence suggests that amyloid polymorphism gives rise to different strains of amyloids with distinct toxicities and pathology-spreading properties. Validating this hypothesis is challenging due to a lack of tools and methods that allow for the direct characterization of amyloid polymorph...
Autores principales: | Cendrowska, Urszula, Silva, Paulo Jacob, Ait-Bouziad, Nadine, Müller, Marie, Guven, Zekiye Pelin, Vieweg, Sophie, Chiki, Anass, Radamaker, Lynn, Kumar, Senthil T., Fändrich, Marcus, Tavanti, Francesco, Menziani, Maria Cristina, Alexander-Katz, Alfredo, Stellacci, Francesco, Lashuel, Hilal A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7104366/ https://www.ncbi.nlm.nih.gov/pubmed/32161130 http://dx.doi.org/10.1073/pnas.1916176117 |
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