Synthesis and antitumor activity against HepG-2, PC-3, and HCT-116 cells of some naphthyridine and pyranopyridinecarbonitrile derivatives

A series of substituted and fused heterocyclic derivatives 2–17 were synthesized using 3,5-bis(4-methoxybenzylidene)-1-propylpiperidin-4-one (1) as starting material. Treatment of 1 with malononitrile or semicarbazide afforded compounds 2 and 3, respectively. Condensation of 1 with ethyl cyanoacetat...

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Detalles Bibliográficos
Autores principales: Mohamed, S. F., Abdel-Hafez, N. A., Amr, A. E., Awad, H. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pleiades Publishing 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7104393/
https://www.ncbi.nlm.nih.gov/pubmed/32288469
http://dx.doi.org/10.1134/S1070363217060226

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7104393/
https://www.ncbi.nlm.nih.gov/pubmed/32288469
http://dx.doi.org/10.1134/S1070363217060226

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