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TGFβ1 orchestrates renal fibrosis following Escherichia coli pyelonephritis

Renal scarring after pyelonephritis is linked to long‐term health risks for hypertension and chronic kidney disease. Androgen exposure increases susceptibility to, and severity of, uropathogenic Escherichia coli (UPEC) pyelonephritis and resultant scarring in both male and female mice, while anti‐an...

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Detalles Bibliográficos
Autores principales: Hreha, Teri N., Collins, Christina A., Daugherty, Allyssa L., Twentyman, Joy, Paluri, Nitin, Hunstad, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7104652/
https://www.ncbi.nlm.nih.gov/pubmed/32227630
http://dx.doi.org/10.14814/phy2.14401