Longitudinal metabolomic analysis of plasma enables modeling disease progression in Duchenne muscular dystrophy mouse models

Duchenne muscular dystrophy is a severe pediatric neuromuscular disorder caused by the lack of dystrophin. Identification of biomarkers is needed to support and accelerate drug development. Alterations of metabolites levels in muscle and plasma have been reported in pre-clinical and clinical cross-s...

Descripción completa

Detalles Bibliográficos
Autores principales: Tsonaka, Roula, Signorelli, Mirko, Sabir, Ekrem, Seyer, Alexandre, Hettne, Kristina, Aartsma-Rus, Annemieke, Spitali, Pietro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
General Article Two
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7104681/
https://www.ncbi.nlm.nih.gov/pubmed/32025735
http://dx.doi.org/10.1093/hmg/ddz309

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7104681/
https://www.ncbi.nlm.nih.gov/pubmed/32025735
http://dx.doi.org/10.1093/hmg/ddz309

Ejemplares similares