Down-Regulation of Fibroblast Growth Factor 2 (FGF2) Contributes to the Premature Senescence of Mouse Embryonic Fibroblast

BACKGROUND: Freshly isolated mouse embryonic fibroblasts (MEFs) have great proliferation capacity but quickly enter senescent state after several rounds of cell cycle, a process called premature senescence. Cellular senescence can be induced by various stresses such as telomere erosion, DNA damage,...

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Detalles Bibliográficos
Autores principales: Li, Jie, Song, Shuo, Li, Xingchao, Zhu, Jing, Li, Wenjuan, Du, Boyu, Guo, Yang, Xi, Xueyan, Han, Rongfei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2020
Materias:
Animal Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7104787/
https://www.ncbi.nlm.nih.gov/pubmed/32188838
http://dx.doi.org/10.12659/MSM.920520

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7104787/
https://www.ncbi.nlm.nih.gov/pubmed/32188838
http://dx.doi.org/10.12659/MSM.920520

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