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Down-Regulation of Fibroblast Growth Factor 2 (FGF2) Contributes to the Premature Senescence of Mouse Embryonic Fibroblast
BACKGROUND: Freshly isolated mouse embryonic fibroblasts (MEFs) have great proliferation capacity but quickly enter senescent state after several rounds of cell cycle, a process called premature senescence. Cellular senescence can be induced by various stresses such as telomere erosion, DNA damage,...
Autores principales: | Li, Jie, Song, Shuo, Li, Xingchao, Zhu, Jing, Li, Wenjuan, Du, Boyu, Guo, Yang, Xi, Xueyan, Han, Rongfei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Scientific Literature, Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7104787/ https://www.ncbi.nlm.nih.gov/pubmed/32188838 http://dx.doi.org/10.12659/MSM.920520 |
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