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IFITM Proteins Incorporated into HIV-1 Virions Impair Viral Fusion and Spread

The interferon-induced transmembrane (IFITM) proteins protect cells from diverse virus infections by inhibiting virus-cell fusion. IFITM proteins also inhibit HIV-1 replication through mechanisms only partially understood. We show that when expressed in uninfected lymphocytes, IFITM proteins exert p...

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Detalles Bibliográficos
Autores principales: Compton, Alex A., Bruel, Timothée, Porrot, Françoise, Mallet, Adeline, Sachse, Martin, Euvrard, Marine, Liang, Chen, Casartelli, Nicoletta, Schwartz, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7104936/
https://www.ncbi.nlm.nih.gov/pubmed/25464829
http://dx.doi.org/10.1016/j.chom.2014.11.001