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Nucleocapsid Phosphorylation and RNA Helicase DDX1 Recruitment Enables Coronavirus Transition from Discontinuous to Continuous Transcription

Coronaviruses contain a positive-sense single-stranded genomic (g) RNA, which encodes nonstructural proteins. Several subgenomic mRNAs (sgmRNAs) encoding structural proteins are generated by template switching from the body transcription regulatory sequence (TRS) to the leader TRS. The process prefe...

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Detalles Bibliográficos
Autores principales: Wu, Chia-Hsin, Chen, Pei-Jer, Yeh, Shiou-Hwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7104987/
https://www.ncbi.nlm.nih.gov/pubmed/25299332
http://dx.doi.org/10.1016/j.chom.2014.09.009