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Targeted therapy guided by single-cell transcriptomic analysis in drug-induced hypersensitivity syndrome/drug reaction with eosinophilia and systemic symptoms: A case report

Drug-induced hypersensitivity syndrome/drug reaction with eosinophilia and systemic symptoms (DiHS/DRESS) is a potentially fatal multi-organ inflammatory disease associated with herpesvirus reactivation and subsequent onset of autoimmune diseases(1–4). Pathophysiology remains elusive and therapeutic...

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Detalles Bibliográficos
Autores principales: Kim, Doyoung, Kobayashi, Tetsuro, Voisin, Benjamin, Jo, Jay-Hyun, Sakamoto, Keiko, Jin, Seon-Pil, Kelly, Michael, Pasieka, Helena B., Naff, Jessica L., Meyerle, Jon H., Ikpeama, Ijeoma D., Fahle, Gary A., Davis, Fred P., Rosenzweig, Sergio D., Alejo, Julie C., Pittaluga, Stefania, Kong, Heidi H., Freeman, Alexandra F., Nagao, Keisuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7105105/
https://www.ncbi.nlm.nih.gov/pubmed/31959990
http://dx.doi.org/10.1038/s41591-019-0733-7