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hPCL3S promotes proliferation and migration of androgen-independent prostate cancer cells

Polycomb repressive complex 2 (PRC2) allows the deposition of H3K27me3. PRC2 facultative subunits modulate its activity and recruitment such as hPCL3/PHF19, a human ortholog of Drosophila Polycomb-like protein (PCL). These proteins contain a TUDOR domain binding H3K36me3, two PHD domains and a “Wing...

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Detalles Bibliográficos
Autores principales: Abdelfettah, Souhila, Boulay, Gaylor, Dubuissez, Marion, Spruyt, Nathalie, Garcia, Sara P., Rengarajan, Shruthi, Loison, Ingrid, Leroy, Xavier, Rivera, Miguel N., Leprince, Dominique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7105160/
https://www.ncbi.nlm.nih.gov/pubmed/32256978
http://dx.doi.org/10.18632/oncotarget.27511