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Co-evolution within structured bacterial communities results in multiple expansion of CRISPR loci and enhanced immunity
Type II CRISPR-Cas systems provide immunity against phages and plasmids that infect bacteria through the insertion of a short sequence from the invader’s genome, known as the ‘spacer’, into the CRISPR locus. Spacers are transcribed into guide RNAs that direct the Cas9 nuclease to its target on the i...
Autores principales: | Pyenson, Nora C, Marraffini, Luciano A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7105378/ https://www.ncbi.nlm.nih.gov/pubmed/32223887 http://dx.doi.org/10.7554/eLife.53078 |
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