Tumors attenuating the mitochondrial activity in T cells escape from PD-1 blockade therapy

PD-1 blockade therapy has revolutionized cancer treatments. However, a substantial population of patients is unresponsive. To rescue unresponsive patients, the mechanism of unresponsiveness to PD-1 blockade therapy must be elucidated. Using a ‘bilateral tumor model’ where responsive and unresponsive...

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Detalles Bibliográficos
Autores principales: Kumar, Alok, Chamoto, Kenji, Chowdhury, Partha S, Honjo, Tasuku
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Immunology and Inflammation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7105382/
https://www.ncbi.nlm.nih.gov/pubmed/32122466
http://dx.doi.org/10.7554/eLife.52330

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7105382/
https://www.ncbi.nlm.nih.gov/pubmed/32122466
http://dx.doi.org/10.7554/eLife.52330

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