Connexin-43 reduction prevents muscle defects in a mouse model of manifesting Duchenne muscular dystrophy female carriers

Duchenne muscular dystrophy (DMD) is a severe X-linked neuromuscular disorder that affects males. However, 8% of female carriers are symptomatic and underrepresented in research due to the lack of animal models. We generated a symptomatic mouse model of DMD carriers via injection of mdx (murine DMD)...

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Detalles Bibliográficos
Autores principales: Nouet, Julie, Himelman, Eric, Lahey, Kevin C., Zhao, Qingshi, Fraidenraich, Diego
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7105483/
https://www.ncbi.nlm.nih.gov/pubmed/32231219
http://dx.doi.org/10.1038/s41598-020-62844-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7105483/
https://www.ncbi.nlm.nih.gov/pubmed/32231219
http://dx.doi.org/10.1038/s41598-020-62844-9

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