Crystal structures of REF6 and its complex with DNA reveal diverse recognition mechanisms

Relative of Early Flowing 6 (REF6) is a DNA-sequence-specific H3K27me3/2 demethylase that contains four zinc finger (ZnF) domains and targets several thousand genes in Arabidopsis thaliana. The ZnF domains are essential for binding target genes, but the structural basis remains unclear. Here, we det...

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Detalles Bibliográficos
Autores principales: Tian, Zizi, Li, Xiaorong, Li, Min, Wu, Wei, Zhang, Manfeng, Tang, Chenjun, Li, Zhihui, Liu, Yunlong, Chen, Zhenhang, Yang, Meiting, Ma, Lulu, Caba, Cody, Tong, Yufeng, Lam, Hon-Ming, Dai, Shaodong, Chen, Zhongzhou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7105484/
https://www.ncbi.nlm.nih.gov/pubmed/32257379
http://dx.doi.org/10.1038/s41421-020-0150-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7105484/
https://www.ncbi.nlm.nih.gov/pubmed/32257379
http://dx.doi.org/10.1038/s41421-020-0150-6

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