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Caloric restriction triggers morphofunctional remodeling of astrocytes and enhances synaptic plasticity in the mouse hippocampus

Calorie-restricted (CR) diet has multiple beneficial effects on brain function. Here we report morphological and functional changes in hippocampal astrocytes in 3-months-old mice subjected to 1 month of the diet. Whole-cell patch-clamp recordings were performed in the CA1 stratum (str.) radiatum ast...

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Detalles Bibliográficos
Autores principales: Popov, Alexander, Denisov, Pavel, Bychkov, Maxim, Brazhe, Alexey, Lyukmanova, Ekaterina, Shenkarev, Zakhar, Lazareva, Natalia, Verkhratsky, Alexei, Semyanov, Alexey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7105492/
https://www.ncbi.nlm.nih.gov/pubmed/32231202
http://dx.doi.org/10.1038/s41419-020-2406-3