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Generation of novel genetically modified rats to reveal the molecular mechanisms of vitamin D actions

Recent studies have suggested that vitamin D activities involve vitamin D receptor (VDR)-dependent and VDR-independent effects of 1α,25-dihydroxyvitamin D(3) (1,25(OH)(2)D(3)) and 25-hydroxyvitamin D(3) (25(OH)D(3)) and ligand-independent effects of the VDR. Here, we describe a novel in vivo system...

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Detalles Bibliográficos
Autores principales: Nishikawa, Miyu, Yasuda, Kaori, Takamatsu, Masashi, Abe, Keisuke, Okamoto, Kairi, Horibe, Kyohei, Mano, Hiroki, Nakagawa, Kimie, Tsugawa, Naoko, Hirota, Yoshihisa, Horie, Tetsuhiro, Hinoi, Eiichi, Okano, Toshio, Ikushiro, Shinichi, Sakaki, Toshiyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7105495/
https://www.ncbi.nlm.nih.gov/pubmed/32231239
http://dx.doi.org/10.1038/s41598-020-62048-1