Nuclear Factor-κB Dysregulation and α-Synuclein Pathology: Critical Interplay in the Pathogenesis of Parkinson’s Disease

The loss of dopaminergic neurons of the nigrostriatal system underlies the onset of the typical motor symptoms of Parkinson’s disease (PD). Lewy bodies (LB) and Lewy neurites (LN), proteinaceous inclusions mainly composed of insoluble α-synuclein (α-syn) fibrils are key neuropathological hallmarks o...

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Detalles Bibliográficos
Autores principales: Bellucci, Arianna, Bubacco, Luigi, Longhena, Francesca, Parrella, Edoardo, Faustini, Gaia, Porrini, Vanessa, Bono, Federica, Missale, Cristina, Pizzi, Marina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7105602/
https://www.ncbi.nlm.nih.gov/pubmed/32265684
http://dx.doi.org/10.3389/fnagi.2020.00068

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7105602/
https://www.ncbi.nlm.nih.gov/pubmed/32265684
http://dx.doi.org/10.3389/fnagi.2020.00068

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