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Ribosomal Protein S6 Hypofunction in Postmortem Human Brain Links mTORC1-Dependent Signaling and Schizophrenia

The mechanistic target of rapamycin (also known as mammalian target of rapamycin) (mTOR)-dependent signaling pathway plays an important role in protein synthesis, cell growth, and proliferation, and has been linked to the development of the central nervous system. Recent studies suggest that mTOR si...

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Detalles Bibliográficos
Autores principales: Ibarra-Lecue, Inés, Diez-Alarcia, Rebeca, Morentin, Benito, Meana, J. Javier, Callado, Luis F., Urigüen, Leyre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7105616/
https://www.ncbi.nlm.nih.gov/pubmed/32265715
http://dx.doi.org/10.3389/fphar.2020.00344