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Ribosomal Protein S6 Hypofunction in Postmortem Human Brain Links mTORC1-Dependent Signaling and Schizophrenia
The mechanistic target of rapamycin (also known as mammalian target of rapamycin) (mTOR)-dependent signaling pathway plays an important role in protein synthesis, cell growth, and proliferation, and has been linked to the development of the central nervous system. Recent studies suggest that mTOR si...
Autores principales: | Ibarra-Lecue, Inés, Diez-Alarcia, Rebeca, Morentin, Benito, Meana, J. Javier, Callado, Luis F., Urigüen, Leyre |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7105616/ https://www.ncbi.nlm.nih.gov/pubmed/32265715 http://dx.doi.org/10.3389/fphar.2020.00344 |
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