Cargando…

The MX-Helix of Muscle nAChR Subunits Regulates Receptor Assembly and Surface Trafficking

Nicotinic acetylcholine receptors (AChRs) are pentameric channels that mediate fast transmission at the neuromuscular junction (NMJ) and defects in receptor expression underlie neuromuscular disorders such as myasthenia gravis and congenital myasthenic syndrome (CMS). Nicotinic receptor expression a...

Descripción completa

Detalles Bibliográficos
Autores principales: Rudell, Jolene Chang, Borges, Lucia Soares, Yarov-Yarovoy, Vladimir, Ferns, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7105636/
https://www.ncbi.nlm.nih.gov/pubmed/32265653
http://dx.doi.org/10.3389/fnmol.2020.00048