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The MX-Helix of Muscle nAChR Subunits Regulates Receptor Assembly and Surface Trafficking
Nicotinic acetylcholine receptors (AChRs) are pentameric channels that mediate fast transmission at the neuromuscular junction (NMJ) and defects in receptor expression underlie neuromuscular disorders such as myasthenia gravis and congenital myasthenic syndrome (CMS). Nicotinic receptor expression a...
Autores principales: | Rudell, Jolene Chang, Borges, Lucia Soares, Yarov-Yarovoy, Vladimir, Ferns, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7105636/ https://www.ncbi.nlm.nih.gov/pubmed/32265653 http://dx.doi.org/10.3389/fnmol.2020.00048 |
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