Neuronal CXCL10/CXCR3 Axis Mediates the Induction of Cerebral Hyperexcitability by Peripheral Viral Challenge

Peripheral infections can potently exacerbate neuropathological conditions, though the underlying mechanisms are poorly understood. We have previously demonstrated that intraperitoneal (i.p.) injection of a viral mimetic, polyinosinic-polycytidylic acid (PIC) induces a robust generation of CXCL10 ch...

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Detalles Bibliográficos
Autores principales: Petrisko, Tiffany J., Bloemer, Jenna, Pinky, Priyanka D., Srinivas, Sriraja, Heslin, Ryan T., Du, Yifeng, Setti, Sharay E., Hong, Hao, Suppiramaniam, Vishnu, Konat, Gregory W., Reed, Miranda N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7105801/
https://www.ncbi.nlm.nih.gov/pubmed/32265633
http://dx.doi.org/10.3389/fnins.2020.00220

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7105801/
https://www.ncbi.nlm.nih.gov/pubmed/32265633
http://dx.doi.org/10.3389/fnins.2020.00220

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