Pathophysiological Role of Transient Receptor Potential Mucolipin Channel 1 in Calcium-Mediated Stress-Induced Neurodegenerative Diseases

Mucolipins (TRPML) are endosome/lysosome Ca(2+) permeable channels belonging to the family of transient receptor potential channels. In mammals, there are three TRPML proteins, TRPML1, 2, and 3, encoded by MCOLN1-3 genes. Among these channels, TRPML1 is a reactive oxygen species sensor localized on...

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Detalles Bibliográficos
Autores principales: Santoni, Giorgio, Maggi, Federica, Amantini, Consuelo, Marinelli, Oliviero, Nabissi, Massimo, Morelli, Maria Beatrice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7105868/
https://www.ncbi.nlm.nih.gov/pubmed/32265740
http://dx.doi.org/10.3389/fphys.2020.00251

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7105868/
https://www.ncbi.nlm.nih.gov/pubmed/32265740
http://dx.doi.org/10.3389/fphys.2020.00251

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