Computational Design of High-Affinity Epitope Scaffolds by Backbone Grafting of a Linear Epitope

Computational grafting of functional motifs onto scaffold proteins is a promising way to engineer novel proteins with pre-specified functionalities. Typically, protein grafting involves the transplantation of protein side chains from a functional motif onto structurally homologous regions of scaffol...

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Detalles Bibliográficos
Autores principales: Azoitei, Mihai L., Ban, Yih-En Andrew, Julien, Jean-Philippe, Bryson, Steve, Schroeter, Alexandria, Kalyuzhniy, Oleksandr, Porter, Justin R., Adachi, Yumiko, Baker, David, Pai, Emil F., Schief, William R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7105911/
https://www.ncbi.nlm.nih.gov/pubmed/22061265
http://dx.doi.org/10.1016/j.jmb.2011.10.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7105911/
https://www.ncbi.nlm.nih.gov/pubmed/22061265
http://dx.doi.org/10.1016/j.jmb.2011.10.003

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