The small chain fatty acid butyrate antagonizes the TCR-stimulation-induced metabolic shift in murine epidermal gamma delta T cells

The metabolic requirements change during cell proliferation and differentiation. Upon antigen-stimulation, effector T cells switch from adenosine-triphospate (ATP)-production by oxidative phosphorylation in the mitochondria to glycolysis. In the gut it was shown that short chain fatty acids (SCFA),...

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Detalles Bibliográficos
Autores principales: Häselbarth, Lukas, Ouwens, D. Margriet, Teichweyde, Nadine, Hochrath, Katrin, Merches, Katja, Esser, Charlotte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Leibniz Research Centre for Working Environment and Human Factors 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7105938/
https://www.ncbi.nlm.nih.gov/pubmed/32256272
http://dx.doi.org/10.17179/excli2020-1123

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7105938/
https://www.ncbi.nlm.nih.gov/pubmed/32256272
http://dx.doi.org/10.17179/excli2020-1123

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