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The small chain fatty acid butyrate antagonizes the TCR-stimulation-induced metabolic shift in murine epidermal gamma delta T cells
The metabolic requirements change during cell proliferation and differentiation. Upon antigen-stimulation, effector T cells switch from adenosine-triphospate (ATP)-production by oxidative phosphorylation in the mitochondria to glycolysis. In the gut it was shown that short chain fatty acids (SCFA),...
Autores principales: | Häselbarth, Lukas, Ouwens, D. Margriet, Teichweyde, Nadine, Hochrath, Katrin, Merches, Katja, Esser, Charlotte |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Leibniz Research Centre for Working Environment and Human Factors
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7105938/ https://www.ncbi.nlm.nih.gov/pubmed/32256272 http://dx.doi.org/10.17179/excli2020-1123 |
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