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Sorafenib induces autophagy and suppresses activation of human macrophage

BACKGROUND: Sorafenib, a multi-kinase inhibitor approved for treatment of advanced renal cell carcinoma and other malignancies, has been shown as a modulator for dendritic cells. This study was designed to examine the effects of sorafenib on macrophages, the major ontogeny of innate immunity. MATERI...

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Detalles Bibliográficos
Autores principales: Lin, Jiunn-Chang, Liu, Chien-Liang, Lee, Jie-Jen, Liu, Tsan-Pai, Ko, Wen-Chin, Huang, Yu-Chuen, Wu, Chih-Hsiung, Chen, Yu-Jen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7106104/
https://www.ncbi.nlm.nih.gov/pubmed/23337882
http://dx.doi.org/10.1016/j.intimp.2013.01.006