Characteristics of DNMT3A mutations in acute myeloid leukemia

BACKGROUND: DNMT3A mutations occur in approximately 20% of AML cases and are associated with changes in DNA methylation. CDKN2B plays an important role in the regulation of hematopoietic progenitor cells and DNMT3A mutation is associated with CDKN2B promoter methylation. We analyzed the characterist...

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Detalles Bibliográficos
Autores principales: Park, Dong Jin, Kwon, Ahlm, Cho, Byung-Sik, Kim, Hee-Je, Hwang, Kyung-Ah, Kim, Myungshin, Kim, Yonggoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society of Hematology; Korean Society of Blood and Marrow Transplantation; Korean Society of Pediatric Hematology-Oncology; Korean Society on Thrombosis and Hemostasis 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7106122/
https://www.ncbi.nlm.nih.gov/pubmed/32269971
http://dx.doi.org/10.5045/br.2020.55.1.17

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7106122/
https://www.ncbi.nlm.nih.gov/pubmed/32269971
http://dx.doi.org/10.5045/br.2020.55.1.17

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