A human microsatellite DNA-mimicking oligodeoxynucleotide with CCT repeats negatively regulates TLR7/9-mediated innate immune responses via selected TLR pathways

A human microsatellite DNA-mimicking ODN (MS ODN) composed of CCT repeats, designated as SAT05f, has been studied for its capacity of negatively regulating innate immunity induced by TLR7/TLR9 agonists in vitro and in mice. The result showed that SAT05f could down-regulate TLR7/9-dependent IFN-α pro...

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Detalles Bibliográficos
Autores principales: Sun, Ran, Sun, Luguo, Bao, Musheng, Zhang, Yongsheng, Wang, Li, Wu, Xiuli, Hu, Dali, Liu, Yongjun, Yu, Yongli, Wang, Liying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. Published by Elsevier Inc. 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7106173/
https://www.ncbi.nlm.nih.gov/pubmed/20034855
http://dx.doi.org/10.1016/j.clim.2009.11.009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7106173/
https://www.ncbi.nlm.nih.gov/pubmed/20034855
http://dx.doi.org/10.1016/j.clim.2009.11.009

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