Cargando…

A human microsatellite DNA-mimicking oligodeoxynucleotide with CCT repeats negatively regulates TLR7/9-mediated innate immune responses via selected TLR pathways

A human microsatellite DNA-mimicking ODN (MS ODN) composed of CCT repeats, designated as SAT05f, has been studied for its capacity of negatively regulating innate immunity induced by TLR7/TLR9 agonists in vitro and in mice. The result showed that SAT05f could down-regulate TLR7/9-dependent IFN-α pro...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sun, Ran, Sun, Luguo, Bao, Musheng, Zhang, Yongsheng, Wang, Li, Wu, Xiuli, Hu, Dali, Liu, Yongjun, Yu, Yongli, Wang, Liying
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier Inc. Published by Elsevier Inc. 2010
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7106173/ https://www.ncbi.nlm.nih.gov/pubmed/20034855 http://dx.doi.org/10.1016/j.clim.2009.11.009

Ejemplares similares

Anti-SARS-CoV immunity induced by a novel CpG oligodeoxynucleotide
por: Bao, Musheng, et al.
Publicado: (2006)

Eicosanoids in the Innate Immune Response: TLR and Non-TLR Routes
por: Alvarez, Yolanda, et al.
Publicado: (2010)

Synthetic Human TLR9-LRR11 Peptide Attenuates TLR9 Signaling by Binding to and thus Decreasing Internalization of CpG Oligodeoxynucleotides
por: Pan, Xichun, et al.
Publicado: (2016)

A microsatellite DNA-derived oligodeoxynucleotide attenuates lipopolysaccharide-induced acute lung injury in mice by inhibiting the HMGB1-TLR4-NF-κB signaling pathway
por: Zhang, Chenghua, et al.
Publicado: (2022)

Development of CpG-Oligodeoxynucleotides for Effective Activation of Rabbit TLR9 Mediated Immune Responses
por: Chuang, Tsung-Hsien, et al.
Publicado: (2014)

CpG-oligodeoxynucleotides developed for grouper toll-like receptor (TLR) 21s effectively activate mouse and human TLR9s mediated immune responses
por: Yeh, Da-Wei, et al.
Publicado: (2017)

The Effect of TLR9 Agonist CpG Oligodeoxynucleotides on the Intestinal Immune Response of Cobia (Rachycentron canadum)
por: Byadgi, Omkar, et al.
Publicado: (2014)

PIKfyve Regulates the Endosomal Localization of CpG Oligodeoxynucleotides to Elicit TLR9-Dependent Cellular Responses
por: Hazeki, Kaoru, et al.
Publicado: (2013)

Interaction of TLR4 and TLR8 in the Innate Immune Response against Mycobacterium Tuberculosis
por: Thada, Shruthi, et al.
Publicado: (2021)

Innate Immune Receptors in Human Airway Smooth Muscle Cells: Activation by TLR1/2, TLR3, TLR4, TLR7 and NOD1 Agonists
por: Månsson Kvarnhammar, Anne, et al.
Publicado: (2013)

Innate Immune Response to Streptococcus pyogenes Depends on the Combined Activation of TLR13 and TLR2
por: Fieber, Christina, et al.
Publicado: (2015)

The Role of the Oxidative State and Innate Immunity Mediated by TLR7 and TLR9 in Lupus Nephritis
por: Echavarria, Raquel, et al.
Publicado: (2023)

Association of GT microsatellite polymorphism in TLR 2 gene with leprosy
por: Suryadevara, NC, et al.
Publicado: (2012)

A Specific Oligodeoxynucleotide Promotes the Differentiation of Osteoblasts via ERK and p38 MAPK Pathways
por: Hou, Xu, et al.
Publicado: (2012)

Identification of a Novel Osteogenetic Oligodeoxynucleotide (osteoDN) That Promotes Osteoblast Differentiation in a TLR9-Independent Manner
por: Nihashi, Yuma, et al.
Publicado: (2022)

Expression of TLR2, TLR4, and TLR9 in dermatomyositis and polymyositis
por: Kim, Geun-Tae, et al.
Publicado: (2009)

Impaired Innate Immunity in Tlr4 (−/−) Mice but Preserved CD8(+) T Cell Responses against Trypanosoma cruzi in Tlr4-, Tlr2-, Tlr9- or Myd88-Deficient Mice
por: Oliveira, Ana-Carolina, et al.
Publicado: (2010)

The Emerging Role of TLR and Innate Immunity in Cardiovascular Disease
por: Spirig, Rolf, et al.
Publicado: (2012)

TLR2 – an innate immune checkpoint in multiple sclerosis
por: Hossain, Md Jakir, et al.
Publicado: (2015)

TLR Cross-talk Confers Specificity to Innate Immunity
por: Tan, Rebecca S. T., et al.
Publicado: (2014)

Local Innate Responses to TLR Ligands in the Chicken Trachea
por: Barjesteh, Neda, et al.
Publicado: (2016)

Common and specific downstream signaling targets controlled by Tlr2 and Tlr5 innate immune signaling in zebrafish
por: Yang, Shuxin, et al.
Publicado: (2015)

TLR9 Ligand (CpG Oligodeoxynucleotide) Induces CLL B-Cells to Differentiate into CD20(+) Antibody-Secreting Cells
por: Ghamlouch, Hussein, et al.
Publicado: (2014)

Delivery System of CpG Oligodeoxynucleotides through Eliciting an Effective T cell Immune Response against Melanoma in Mice
por: Sun, Wei, et al.
Publicado: (2016)

An Oligodeoxynucleotide with Promising Modulation Activity for the Proliferation and Activation of Osteoblast
por: Feng, Zhiyuan, et al.
Publicado: (2011)

The Role of TLR2, TLR4, and TLR9 in the Pathogenesis of Atherosclerosis
por: Roshan, Mohsin H. K., et al.
Publicado: (2016)

An Oligodeoxynucleotide That Induces Differentiation of Bone Marrow Mesenchymal Stem Cells to Osteoblasts in Vitro and Reduces Alveolar Bone Loss in Rats with Periodontitis
por: Shen, Yuqin, et al.
Publicado: (2012)

Novel oligodeoxynucleotide agonists of TLR9 containing N(3)-Me-dC or N(1)-Me-dG modifications
por: Putta, Mallikarjuna Reddy, et al.
Publicado: (2006)

Cytidine-phosphate-guanosine oligodeoxynucleotides in combination with CD40 ligand decrease periodontal inflammation and alveolar bone loss in a TLR9-independent manner
por: Zhao, Qian, et al.
Publicado: (2018)

Viruses utilize ubiquitination systems to escape TLR/RLR-mediated innate immunity
por: Huang, Shanzhi, et al.
Publicado: (2022)

Transcriptome sequencing of microglial cells stimulated with TLR3 and TLR4 ligands
por: Das, Amitabh, et al.
Publicado: (2015)

The effect of the TLR9 ligand CpG-oligodeoxynucleotide on the protective immune response to alcelaphine herpesvirus-1-mediated malignant catarrhal fever in cattle
por: Parameswaran, Nevi, et al.
Publicado: (2014)

Modulation of Innate Immune Responses via Covalently Linked TLR Agonists
por: Tom, Janine K., et al.
Publicado: (2015)

Activation of a TLR9 mediated innate immune response in preeclampsia
por: Williamson, Rachel D., et al.
Publicado: (2019)

Rewiring innate and adaptive immunity with TLR9 agonist to treat osteosarcoma
por: Cascini, Caterina, et al.
Publicado: (2023)

Study of TLR3, TLR4 and TLR9 in breast carcinomas and their association with metastasis
por: González-Reyes, Salomé, et al.
Publicado: (2010)

Pathogen-associated selection on innate immunity genes (TLR4, TLR7) in a neotropical rodent in landscapes differing in anthropogenic disturbance
por: Heni, Alexander Christoph, et al.
Publicado: (2020)

Production of IFN-γ by splenic dendritic cells during innate immune responses against Francisella tularensis LVS depends on MyD88, but not TLR2, TLR4, or TLR9
por: De Pascalis, Roberto, et al.
Publicado: (2020)

The molecular basis for recognition of bacterial ligands at equine TLR2, TLR1 and TLR6
por: Irvine, Katherine Lucy, et al.
Publicado: (2013)

Epithelial and Stromal Cells of Bovine Endometrium Have Roles in Innate Immunity and Initiate Inflammatory Responses to Bacterial Lipopeptides In Vitro via Toll-Like Receptors TLR2, TLR1, and TLR6
por: Turner, Matthew L., et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_65jd53jj0g4n0sj5kjfm2kpkl3