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Viral proteome size and CD8+ T cell epitope density are correlated: The effect of complexity on selection

The relation between the complexity of organisms and proteins and their evolution rates has been discussed in the context of multiple generic models. The main robust claim from most such models is the negative relation between complexity and the accumulation rate of mutations. Viruses accumulate esc...

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Detalles Bibliográficos
Autores principales: Agranovich, Alexandra, Maman, Yaakov, Louzoun, Yoram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7106205/
https://www.ncbi.nlm.nih.gov/pubmed/23954420
http://dx.doi.org/10.1016/j.meegid.2013.07.030