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Phase I Clinical Trial of Autologous Ascites-derived Exosomes Combined With GM-CSF for Colorectal Cancer

Exosomes are small membrane vesicles that are secreted by a multitude of cell types. The exosomes derived from dendritic cells (Dex), tumor cells (Tex), and malignant effusions demonstrate immunomodulatory functions, and are even under clinical trial for cancer treatments. In this study we report th...

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Detalles Bibliográficos
Autores principales: Dai, Shengming, Wei, Dong, Wu, Zhen, Zhou, Xiangyang, Wei, Xiaomou, Huang, Haixin, Li, Guisheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Gene Therapy. Published by Elsevier Inc. 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7106337/
https://www.ncbi.nlm.nih.gov/pubmed/18362931
http://dx.doi.org/10.1038/mt.2008.1