Cargando…

Phase I Clinical Trial of Autologous Ascites-derived Exosomes Combined With GM-CSF for Colorectal Cancer

Exosomes are small membrane vesicles that are secreted by a multitude of cell types. The exosomes derived from dendritic cells (Dex), tumor cells (Tex), and malignant effusions demonstrate immunomodulatory functions, and are even under clinical trial for cancer treatments. In this study we report th...

Descripción completa

Detalles Bibliográficos
Autores principales:	Dai, Shengming, Wei, Dong, Wu, Zhen, Zhou, Xiangyang, Wei, Xiaomou, Huang, Haixin, Li, Guisheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society of Gene Therapy. Published by Elsevier Inc. 2008
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7106337/ https://www.ncbi.nlm.nih.gov/pubmed/18362931 http://dx.doi.org/10.1038/mt.2008.1

Ejemplares similares

HSP70 interacts with TRAF2 and differentially regulates TNFα signalling in human colon cancer cells
por: Dai, Shengming, et al.
Publicado: (2010)

Construction of Recombinant Human GM-CSF and GM-CSF-ApoA-I Fusion Protein and Evaluation of Their Biological Activity
por: Pykhtina, Mariya, et al.
Publicado: (2021)

GM-CSF in inflammation
por: Hamilton, John A.
Publicado: (2019)

G-CSF and GM-CSF in clinical trials.
por: Antman, K. H.
Publicado: (1990)

GM-CSF facilitates the development of inflammation-associated colorectal carcinoma
por: Chen, Guojiang, et al.
Publicado: (2014)

Recombinant GM-CSF for diseases of GM-CSF insufficiency: Correcting dysfunctional mononuclear phagocyte disorders
por: Lazarus, Hillard M., et al.
Publicado: (2023)

G‐CSF/GM‐CSF‐induced hematopoietic dysregulation in the progression of solid tumors
por: He, Kai, et al.
Publicado: (2022)

iNKT Cell Production of GM-CSF Controls Mycobacterium tuberculosis
por: Rothchild, Alissa C., et al.
Publicado: (2014)

A role for G-CSF and GM-CSF in nonmyeloid cancers
por: Aliper, Alexander M, et al.
Publicado: (2014)

GM-CSF-Dependent Inflammatory Pathways
por: Hamilton, John A.
Publicado: (2019)

Development of Dendritic Cells from GM-CSF(-/-) Mice in vitro : GM-CSF Enhances Production and Survival of Cells
por: Ni, Keping, et al.
Publicado: (2001)

Blockade of collagen-induced arthritis post-onset by antibody to granulocyte-macrophage colony-stimulating factor (GM-CSF): requirement for GM-CSF in the effector phase of disease
por: Cook, Andrew D, et al.
Publicado: (2001)

Combination of IFN-α/Gm-CSF as a Maintenance Therapy for Multiple Myeloma Patients After Autologous Stem Cell Transplantation (ASCT): A Prospective Phase II Study
por: Salmasinia, Donya, et al.
Publicado: (2010)

Response to Treatment with TNFα Inhibitors in Rheumatoid Arthritis Is Associated with High Levels of GM-CSF and GM-CSF(+) T Lymphocytes
por: Bystrom, Jonas, et al.
Publicado: (2017)

Phase I/II study of GM-CSF DNA as an adjuvant for a multipeptide cancer vaccine in patients with advanced melanoma
por: Perales, Miguel-Angel, et al.
Publicado: (2008)

EPCT-18. PHASE 0/I STUDY OF GM-CSF AND INTRATHECAL TRASTUZUMAB IN CHILDREN WITH RECURRENT POSTERIOR FOSSA EPENDYMOMA
por: Dorris, Kathleen, et al.
Publicado: (2020)

Diagnosis, prognosis and bioinformatics analysis of lncRNAs in hepatocellular carcinoma
por: Dai, Meiyu, et al.
Publicado: (2017)

Pivotal Roles of GM-CSF in Autoimmunity and Inflammation
por: Shiomi, Aoi, et al.
Publicado: (2015)

A Review of GM-CSF Therapy in Sepsis
por: Mathias, Brittany, et al.
Publicado: (2015)

The efficacy and safety of targeting GM-CSF in arthritis
por: Bykerk, Vivian P
Publicado: (2020)

GM-CSF: Orchestrating the Pulmonary Response to Infection
por: McCormick, Thomas S., et al.
Publicado: (2022)

Role of GM-CSF in lung balance and disease
por: Chen, Yingzi, et al.
Publicado: (2023)

Loss of GM-CSF-dependent instruction of alveolar macrophages in COVID-19 provides a rationale for inhaled GM-CSF treatment
por: Bosteels, Cedric, et al.
Publicado: (2022)

Glutamine Deprivation Promotes the Generation and Mobilization of MDSCs by Enhancing Expression of G-CSF and GM-CSF
por: Sun, Hong-Wei, et al.
Publicado: (2021)

Phase III randomized, double-blinded, placebo-controlled multicenter trial of melapuldencil-t: autologous dendritic cells loaded with irradiated autologous tumor cells (dc-tc) in gm-csf in patients with metastatic melanoma
por: Dillman, Robert, et al.
Publicado: (2014)

Evaluation of Pre-Treatment Serum Levels of IL-7 and GM-CSF in Colorectal Cancer Patients
por: Taghipour Fard Ardekani, Mehdi, et al.
Publicado: (2014)

Functional characterization of GM-CSF induced monocyte subsets
por: Däbritz, J, et al.
Publicado: (2008)

G-CSF and GM-CSF Modify Neutrophil Functions at Concentrations found in Cystic Fibrosis
por: Castellani, Stefano, et al.
Publicado: (2019)

Delivery of GM-CSF to Protect against Influenza Pneumonia
por: Subramaniam, Renuka, et al.
Publicado: (2015)

GM-CSF as a therapeutic target in autoimmune diseases
por: Shiomi, Aoi, et al.
Publicado: (2016)

Roles of GM-CSF in the Pathogenesis of Autoimmune Diseases: An Update
por: Lotfi, Noushin, et al.
Publicado: (2019)

GM-CSF: A Promising Target in Inflammation and Autoimmunity
por: Lee, Kevin M C, et al.
Publicado: (2020)

GM-CSF Dependent Differential Control of Mycobacterium tuberculosis Infection in Human and Mouse Macrophages: Is Macrophage Source of GM-CSF Critical to Tuberculosis Immunity?
por: Mishra, Abhishek, et al.
Publicado: (2020)

Phase II clinical trial evaluating docetaxel, vinorelbine and GM-CSF in stage IV melanoma
por: Eroglu, Zeynep, et al.
Publicado: (2011)

Fusion Expression and Immune Effect of PCV2 Cap Protein Tandem Multiantigen Epitopes with CD154/GM-CSF
por: Mao, Qian, et al.
Publicado: (2021)

Irradiated Bladder Cancer Cells Expressing both GM-CSF and IL-21 versus Either GM-CSF or IL-21 Alone as Tumor Vaccine in a Mouse Xenograft Model
por: Peng, Junming, et al.
Publicado: (2019)

Determinants of a transcriptionally competent environment at the GM-CSF promoter
por: Brettingham-Moore, K. H., et al.
Publicado: (2008)

Clinical uses of GM-CSF, a critical appraisal and update
por: Arellano, Martha, et al.
Publicado: (2008)

Retrovirus mediated transfer and expression of GM-CSF in haematopoietic cells.
por: Keith, W. N., et al.
Publicado: (1990)

Deficiencies of GM-CSF and Interferon γ Link Inflammation and Cancer
por: Enzler, Thomas, et al.
Publicado: (2003)

Cannot write session to /tmp/vufind_sessions/sess_f5uh4proq79q3qoc4age68gl5p