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Inhibitory and Coactivating Receptors Recognising the Same Ligand: Immune Homeostasis Exploited by Pathogens and Tumours

Coactivating and inhibitory receptors that share at least one ligand interact with a wide variety of ligands, indicating their importance in a range of situations. Here, we discuss principles of mainly human paired receptor function and ligand recognition, and possible therapeutic implications of ta...

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Detalles Bibliográficos
Autores principales: Levi-Schaffer, Francesca, Mandelboim, Ofer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7106362/
https://www.ncbi.nlm.nih.gov/pubmed/29066058
http://dx.doi.org/10.1016/j.it.2017.10.001