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Computational characterization and design of SARS coronavirus receptor recognition and antibody neutralization

The sequential determination of crystal structures of the SARS coronavirus spike receptor-binding domain (RBD) in complex with its cellular receptor or neutralizing antibody opened a door for the design and development of antiviral competitive inhibitors. Based on those complex structures, we conduc...

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Detalles Bibliográficos
Autores principales: Zhang, Yuan, Zheng, Nan, Zhong, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7106420/
https://www.ncbi.nlm.nih.gov/pubmed/17374510
http://dx.doi.org/10.1016/j.compbiolchem.2007.02.005