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Transcriptional control of regulatory T cell development and function

Regulatory T (Treg) cells differentiate from thymocytes or peripheral T cells in response to host and environmental cues, culminating in induction of the transcription factor forkhead box P3 (Foxp3) and the Treg cell-specific epigenome. An intermediate amount of antigen stimulation is required to in...

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Detalles Bibliográficos
Autores principales: Luo, Chong T., Li, Ming O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7106436/
https://www.ncbi.nlm.nih.gov/pubmed/24016547
http://dx.doi.org/10.1016/j.it.2013.08.003