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De-O-Acetylation of mucin-derived sialic acids by recombinant NanS-p esterases of Escherichia coli O157:H7 strain EDL933

Enterohemorrhagic Escherichia coli (EHEC) O157:H7 strain EDL933 encodes the single chromosomal 9-O-acetylesterase NanS, and several copies of prophage-encoded 9-O-acetylesterases (NanS-p). These enzymes have recently been shown to cleave 5-N-acetyl-9-O-acetyl neuraminic acid (Neu5,9Ac(2)) to yield d...

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Detalles Bibliográficos
Autores principales: Feuerbaum, S., Saile, N., Pohlentz, G., Müthing, J., Schmidt, H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier GmbH. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7106450/
https://www.ncbi.nlm.nih.gov/pubmed/30340996
http://dx.doi.org/10.1016/j.ijmm.2018.10.001