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The risks of targeting co-inhibitory pathways to modulate pathogen-directed T cell responses
The identification of T cell co-inhibition as a central mechanism in the regulation of adaptive immunity during infectious diseases provides new opportunities for immunotherapeutic interventions. However, the fact that T cell activity is frequently downregulated during pathogen-directed responses su...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier Ltd.
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7106470/ https://www.ncbi.nlm.nih.gov/pubmed/23333205 http://dx.doi.org/10.1016/j.it.2012.12.002 |