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Molecular dynamics of Middle East Respiratory Syndrome Coronavirus (MERS CoV) fusion heptad repeat trimers

Structural studies related to Middle East Respiratory Syndrome Coronavirus (MERS CoV) infection process are so limited. In this study, molecular dynamics (MD) simulations were carried out to unravel changes in the MERS CoV heptad repeat domains (HRs) and factors affecting fusion state HR stability....

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Detalles Bibliográficos
Autores principales: Kandeel, Mahmoud, Al-Taher, Abdulla, Li, Huifang, Schwingenschlogl, Udo, Al-Nazawi, Mohamed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7106505/
https://www.ncbi.nlm.nih.gov/pubmed/29803965
http://dx.doi.org/10.1016/j.compbiolchem.2018.05.020