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Small-molecule inhibitors as potential therapeutics and as tools to understand the role of phospholipases A(2)()

Phospholipase A(2) (PLA(2)) enzymes are involved in various inflammatory pathological conditions including arthritis, cardiovascular and autoimmune diseases. The regulation of their catalytic activity is of high importance and a great effort has been devoted in developing synthetic inhibitors. We su...

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Detalles Bibliográficos
Autores principales: Nikolaou, Aikaterini, Kokotou, Maroula G., Vasilakaki, Sofia, Kokotos, George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7106526/
https://www.ncbi.nlm.nih.gov/pubmed/30905350
http://dx.doi.org/10.1016/j.bbalip.2018.08.009