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The histone demethylase JMJD2A promotes glioma cell growth via targeting Akt-mTOR signaling

BACKGROUND: A number of JmjC domain-containing histone demethylases have been identified and biochemically characterized in mammalian models and humans. JMJD2A is a transcriptional co-factor and enzyme that catalyzes the demethylation of histone H3 lysine 9 and 36 (H3K9 and H3K36). Here in this stud...

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Detalles Bibliográficos
Autores principales: Li, Min, Cheng, Jingmin, Ma, Yuan, Guo, Heng, Shu, Haifeng, Huang, Haidong, Kuang, Yongqin, Yang, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7106579/
https://www.ncbi.nlm.nih.gov/pubmed/32256210
http://dx.doi.org/10.1186/s12935-020-01177-z