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The histone demethylase JMJD2A promotes glioma cell growth via targeting Akt-mTOR signaling
BACKGROUND: A number of JmjC domain-containing histone demethylases have been identified and biochemically characterized in mammalian models and humans. JMJD2A is a transcriptional co-factor and enzyme that catalyzes the demethylation of histone H3 lysine 9 and 36 (H3K9 and H3K36). Here in this stud...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7106579/ https://www.ncbi.nlm.nih.gov/pubmed/32256210 http://dx.doi.org/10.1186/s12935-020-01177-z |