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Enhancing the bioconversion of phytosterols to steroidal intermediates by the deficiency of kasB in the cell wall synthesis of Mycobacterium neoaurum

BACKGROUND: The bioconversion of phytosterols into high value-added steroidal intermediates, including the 9α-hydroxy-4-androstene-3,17-dione (9-OHAD) and 22-hydroxy-23,24-bisnorchol-4-ene-3-one (4-HBC), is the cornerstone in steroid pharmaceutical industry. However, the low transportation efficienc...

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Detalles Bibliográficos
Autores principales: Xiong, Liang-Bin, Liu, Hao-Hao, Zhao, Ming, Liu, Yong-Jun, Song, Lu, Xie, Zhi-Yong, Xu, Yi-Xin, Wang, Feng-Qing, Wei, Dong-Zhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7106593/
https://www.ncbi.nlm.nih.gov/pubmed/32228591
http://dx.doi.org/10.1186/s12934-020-01335-y