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Enhancing the bioconversion of phytosterols to steroidal intermediates by the deficiency of kasB in the cell wall synthesis of Mycobacterium neoaurum
BACKGROUND: The bioconversion of phytosterols into high value-added steroidal intermediates, including the 9α-hydroxy-4-androstene-3,17-dione (9-OHAD) and 22-hydroxy-23,24-bisnorchol-4-ene-3-one (4-HBC), is the cornerstone in steroid pharmaceutical industry. However, the low transportation efficienc...
Autores principales: | Xiong, Liang-Bin, Liu, Hao-Hao, Zhao, Ming, Liu, Yong-Jun, Song, Lu, Xie, Zhi-Yong, Xu, Yi-Xin, Wang, Feng-Qing, Wei, Dong-Zhi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7106593/ https://www.ncbi.nlm.nih.gov/pubmed/32228591 http://dx.doi.org/10.1186/s12934-020-01335-y |
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