Cytotoxic T lymphocyte-associated antigen-4-Ig (CTLA-4-Ig) suppresses Staphylococcus aureus-induced CD80, CD86, and pro-inflammatory cytokine expression in human B cells

BACKGROUND: Cytotoxic T lymphocyte-associated antigen-4-Ig (CTLA-4-Ig) competes with CD28 for binding CD80/CD86 on antigen-presenting cells (APCs) to limit T cell activation. B cells are believed to be important APCs in the pathogenesis of autoimmune diseases and express CD80/CD86 after activation;...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Po-Chun, Ssu, Chih-Tai, Tsao, Yen-Po, Liou, Teh-Ling, Tsai, Chang-Youh, Chou, Chung-Tei, Chen, Ming-Han, Leu, Chuen-Miin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7106629/
https://www.ncbi.nlm.nih.gov/pubmed/32228715
http://dx.doi.org/10.1186/s13075-020-2138-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7106629/
https://www.ncbi.nlm.nih.gov/pubmed/32228715
http://dx.doi.org/10.1186/s13075-020-2138-x

Ejemplares similares