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Cytotoxic T lymphocyte-associated antigen-4-Ig (CTLA-4-Ig) suppresses Staphylococcus aureus-induced CD80, CD86, and pro-inflammatory cytokine expression in human B cells

BACKGROUND: Cytotoxic T lymphocyte-associated antigen-4-Ig (CTLA-4-Ig) competes with CD28 for binding CD80/CD86 on antigen-presenting cells (APCs) to limit T cell activation. B cells are believed to be important APCs in the pathogenesis of autoimmune diseases and express CD80/CD86 after activation;...

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Detalles Bibliográficos
Autores principales:	Liu, Po-Chun, Ssu, Chih-Tai, Tsao, Yen-Po, Liou, Teh-Ling, Tsai, Chang-Youh, Chou, Chung-Tei, Chen, Ming-Han, Leu, Chuen-Miin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7106629/ https://www.ncbi.nlm.nih.gov/pubmed/32228715 http://dx.doi.org/10.1186/s13075-020-2138-x

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