BRCA1 and homologous recombination: implications from mouse embryonic development

As an important player in DNA damage response, BRCA1 maintains genomic stability and suppresses tumorigenesis by promoting DNA double-strand break (DSB) repair through homologous recombination (HR). Since the cloning of BRCA1 gene, many Brca1 mutant alleles have been generated in mice. Mice carrying...

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Detalles Bibliográficos
Autores principales: Liu, Yidan, Lu, Lin-Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7106644/
https://www.ncbi.nlm.nih.gov/pubmed/32257107
http://dx.doi.org/10.1186/s13578-020-00412-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7106644/
https://www.ncbi.nlm.nih.gov/pubmed/32257107
http://dx.doi.org/10.1186/s13578-020-00412-4

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