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CHD4 mediates proliferation and migration of non-small cell lung cancer via the RhoA/ROCK pathway by regulating PHF5A

BACKGROUND: Chromodomain helicase DNA-binding protein 4 (CHD4) has been shown to contribute to DNA repair and cell cycle promotion; however, its roles in cancer initiation and progression remain largely unknown. This study aimed to demonstrate the role of CHD4 in the development of non-small cell lu...

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Detalles Bibliográficos
Autores principales: Xu, Nuo, Liu, Fanglei, Wu, Shengdi, Ye, Maosong, Ge, Haiyan, Zhang, Meiling, Song, Yuanlin, Tong, Lin, Zhou, Jian, Bai, Chunxue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7106713/
https://www.ncbi.nlm.nih.gov/pubmed/32228507
http://dx.doi.org/10.1186/s12885-020-06762-z