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Comparison of pathogenicity of subtype H9 avian influenza wild-type viruses from a wide geographic origin expressing mono-, di-, or tri-basic hemagglutinin cleavage sites

An intravenous pathogenicity index (IVPI) of > 1.2 in chickens or, in case of subtypes H5 and H7, expression of a polybasic hemagglutinin cleavage site (HACS), signals high pathogenicity (HP). Viruses of the H9N2-G1 lineage, which spread across Asia and Africa, are classified to be of low pathoge...

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Detalles Bibliográficos
Autores principales: Parvin, Rokshana, Schinkoethe, Jan, Grund, Christian, Ulrich, Reiner, Bönte, Franziska, Behr, Klaus P., Voss, Matthias, Samad, Mohammed A., Hassan, Kareem E., Luttermann, Christine, Beer, Martin, Harder, Timm
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7106749/
https://www.ncbi.nlm.nih.gov/pubmed/32234073
http://dx.doi.org/10.1186/s13567-020-00771-3