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ADAM10 promotes cell growth, migration, and invasion in osteosarcoma via regulating E-cadherin/β-catenin signaling pathway and is regulated by miR-122-5p

BACKGROUND: Osteosarcoma is a malignant bone tumor. Increasing evidences have revealed that a disintegrin and metalloproteinase 10 (ADAM10) is implicated in tumor development. The main purpose of this study is to explore the effects of ADAM10 on osteosarcoma cell functions and the underlying molecul...

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Detalles Bibliográficos
Autores principales: Yuan, Quan, Yu, Honghao, Chen, Jianhua, Song, Xiaoyu, Sun, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7106760/
https://www.ncbi.nlm.nih.gov/pubmed/32256208
http://dx.doi.org/10.1186/s12935-020-01174-2