DDX5 potentiates HIV-1 transcription as a co-factor of Tat

BACKGROUND: HIV-1 does not encode a helicase and hijacks those of the cell for efficient replication. We and others previously showed that the DEAD box helicase, DDX5, is an essential HIV dependency factor. DDX5 was recently shown to be associated with the 7SK snRNP. Cellular positive transcription...

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Detalles Bibliográficos
Autores principales: Sithole, Nyaradzai, Williams, Claire A., Abbink, Truus E. M., Lever, Andrew M. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7106839/
https://www.ncbi.nlm.nih.gov/pubmed/32228614
http://dx.doi.org/10.1186/s12977-020-00514-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7106839/
https://www.ncbi.nlm.nih.gov/pubmed/32228614
http://dx.doi.org/10.1186/s12977-020-00514-4

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